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    • Main Office
      Burkert South Africa (PTY) Ltd
      Visitors address:

      233 Albert Amon Road
      Millennium Business Park
      Meadowdale / Germiston

      Mailing address:

      P.O. Box 26260
      East Rand
      1462
      Phone +27 11 574 6000
      Fax +27 11 454 1477
      E-Mail fnyrf.mn@ohexreg.pbz
    • Office
      Durban Branch
      32 Grays-Inn Crescent
      Westville

      Phone +27 31 266 1600
      Fax +27 31 266 1495
      E-Mail fnyrf.mn@ohexreg.pbz
    • Office
      Cape Town Branch
      Unit 26, Northgate Business Park
      Northgate Estate

      Phone +27 21 510 7137
      Fax +27 21 510 7135
      E-Mail fnyrf.mn@ohexreg.pbz
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We make ideas flow.

Biochip analysis

This process is a highly innovative method of molecular-biological analysis.

Biochips are microscopic slides (generally made of glass or a polymer) on which biological material (e.g. oligonucleotides or cDNA) is fixed in large numbers and with a high density, as a single strand in the form of microarrays, i.e. in a defined arrangement.

Such chips perform the function of diagnostic tools and are offered by many manufacturers with various attributes.

In the case of biochip analysis, the substance under investigation, which is also single-strand (e.g. a patient sample or food sample), is brought into contact with the molecules fixed on the chip. If molecules of the sample substance encounter molecules of the chip that are complementary to them, an interaction occurs on the basis of the key-and-lock principle ("precise-fit mating parts"), with formation of a double strand (complementary hybridization). This process can be visualized by appropriate pretreatment of the sample materials with fluorescent dye. The fluorescent pattern thus produced contains the information as to what substances were present in the sample.

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